In addition, many women who suffer from depression, including those who have been effectively treated with an antidepressant, report worsening of their depressive symptoms during the premenstrual phase of the menstrual cycle. Although this may be a consequence of sensitivity to fluctuating hormone levels, little is known about the efficacy of hormonal interventions, including oral contraceptives OCPs , in the treatment of premenstrual worsening of depressive symptoms. These women were years of age and had regular menstrual cycles. All of the women had a depressive disorder major or minor depression or dysthymia and had been doing well on an antidepressant for at least 2 months except for premenstrually, when their depression symptoms would re-emerge. Women with premenstrual worsening of depression were randomized to augmentation of their antidepressant mostly serotonin-based with Yasmin.
The Oral Contraceptive Pill for Premenstrual Worsening of Depression
List of Contraceptives + Types & Side Effects - eushopper.info
An oral contraceptive OC is effective because it delivers high doses of estrogen to prevent ovulation. Unfortunately, some anti-epileptic medications alter the metabolism of birth control pills because they induce a liver enzyme which metabolizes the estrogen contained within the OC. Thus, if a woman is given an anti-epileptic medication along with a birth control pill, her dose of estrogen may be decreased and the OC may cease to be effective. This interaction occurs primarily with oral contraceptive pills, but can also occur with the NuvaRing, a vaginal contraceptive ring, because the hormones contained in these preparations are metabolized by the liver. However, the NuvaRing and oral contraceptives containing estrogen may decrease Lamictal levels. Thus, if you have a woman who has been stable on a given dose of Lamictal who is starting the NuvaRing or an oral contraceptive, she may need to increase her dosage of Lamictal to maintain the same blood level. This is after over 6 years of the patch with absolutely no problems.
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Teenage girls using birth control pills tend to score higher on a measure of depressive symptoms compared with their nonusing counterparts, according to new research published in JAMA Psychiatry. But these symptoms seem to diminish once they enter adulthood. Most women first take an oral contraceptive pill as a teen, and teens have lots of challenging emotional issues to deal with so it especially important to monitor how they are doing.